For the treatment of thrombocytopenia in adult patients with chronic liver disease before a scheduled procedure

About DOPTELET

In 2 Robust Phase 3 Studies

  • Significantly more patients taking DOPTELET reached a platelet count of 50,000/µL compared to placebo (P<.0001)1*
  • Significantly reduced the need for platelet transfusion or any rescue procedure for bleeding compared to placebo (P<.001)1†
  • Safety profile was similar to placebo1

*On procedure day, 10 to 13 days after starting DOPTELET 40 mg or DOPTELET 60 mg once daily for 5 days, compared to placebo (P<.0001; N=435).1

From randomization of DOPTELET 40 mg or DOPTELET 60 mg once daily for 5 days up to 7 days after a procedure, compared to placebo (P<.001; N=435).1

Patients take DOPTELET for 5 days in a row

DOPTELET Increased Patients' Platelet Counts
With 5-Day Oral Dosing

  • As a TPO receptor agonist, DOPTELET stimulates megakaryocytes to increase platelet production1
  • DOPTELET does not block native TPO, allowing for an additive effect1
  • Onset of effect is seen in 3 to 5 days with peak platelet levels achieved after 10 to 13 days1

View the DOPTELET Mechanism of Action

Reference:

1. DOPTELET [package insert]. Durham, NC: Dova Pharmaceuticals, Inc; 2018.

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